Varenicline
نویسندگان
چکیده
منابع مشابه
Mania induced by varenicline
Varenicline is sometimes used in the treatment of smoking addiction. Side effects such as nausea, vomiting, and headaches have been well documented. In addition, depressed mood and suicidal thoughts relating to varenicline usage have been previously reported. We report a case of mania in a patient with refractory depression whose first manic episode developed under the use of varenicline in com...
متن کاملVarenicline: for smoking cessation.
Varenicline, a partial agonist of alpha4beta2 nicotinic acetylcholine receptor (nAChR), is the most recently approved drug for smoking cessation. Despite the availability of effective treatments for smoking cessation, such as nicotine replacement therapy and Bupropion sustained-release, abstinence rates remain less than optimal. As a nAChR partial agonist, Varenicline attenuates the craving and...
متن کاملVarenicline : Where are we today ?
In 2006, Chantix (varenicline) splashed boldly onto the nicotine cessation medication scene with full Food and Drug Administration (FDA) approval following the completion of three distinct Pfizer-funded clinical trials (Jorenby et al., 2006; Gonzales et al., 2006; Tonstad et al., 2006). Almost immediately, however, and contrary to the initial findings supporting the safety and efficacy of varen...
متن کاملSmoking cessation therapy with varenicline
Smoking cessation is the only available intervention proven to halt progression of chronic obstructive pulmonary disease (COPD). The authors discuss the current existing treatment modalities and the role of a newly approved agent, varenicline, in promotion of smoking cessation. Varenicline is a novel agent that is a centrally acting partial nicotinic acetylcholine receptor agonist. It has both ...
متن کاملOral varenicline for smoking cessation.
OBJECTIVE To review the pharmacology, pharmacokinetics, efficacy, and safety of varenicline and provide a review of relevant clinical data. DATA SOURCES A MEDLINE search (2001-December 2006) was conducted using the key words varenicline and nicotine replacement therapy for clinical trials limited to human subjects and published in English. STUDY SELECTION AND DATA EXTRACTION All available h...
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ژورنال
عنوان ژورنال: Australian Prescriber
سال: 2008
ISSN: 0312-8008,1839-3942
DOI: 10.18773/austprescr.2008.035